Repair all holes in buildings that would allow mice from entering.
Open doors and windows before cleaning areas where mice have been living. If possible, run an electric fan for at least half an hour to clear out dust. Leave the area while the fan is on.
Disinfect sites where you have seen mice or their droppings. General-purpose disinfectants will kill the virus. A mixture of 3 tablespoons of household bleach in a gallon of water can also be used. Spray the area and mop, rather than sweeping or vacuuming. The wetter the area, the better because dampness will keep the dust down.
Remember that the territory of mice rarely extends farther than 30 feet from the nest, and more often is about 10 feet. If mice are sighted throughout a building, it means that there are numerous discrete locations where you will have to set traps.
In live traps, oatmeal is a very effective bait. On snap traps, a piece of Slim Jim is almost irresistible to mice. It is much more effective than cheese or peanut butter.
When you find a mouse in a snap trap, spray it with a disinfectant and put it in a plastic bag before disposing of it.
Never use rodenticides for various reasons. First, if a mouse dies where you can't find it, you will have an odor problem. Also, if the mice (particularly deer mice) have ectoparasites such as fleas or mites, they will leave the dead carcass and may attack the human occupants of the house. Mice should always be controlled with snap or live traps.
If you have a crawl space under your house, you should have it rodent-proofed. If you can't do this yourself or prefer not to, seek out a professional to do the work.
